About Rulo

Dr. Nicole Scott, Founder of Rulo SkinRulo’s founder, Nicole Scott, PhD., MPH, brought her passion for health and preventative medicine together with her expertise in the microbiome, to form a company whose sole purpose is to improve the health of all skin, whatever age, concern, or composition that it is.

With a diverse team of physicians and scientists focused on peer-reviewed, evidence-based skin science, Rulo is leading the development of highly-effective skincare products that take a long-term and whole-body view of skin health.

My husband and I suffered from the itching, flaking and broken skin of atopic dermatitis and eczema. Like so many people, we were locked in a constant back and forth between which was worse: the symptoms or the side effects of the treatment. 

Multiple trips to the dermatologist led us to a journey of over-the-counter solutions and prescriptions. All of them were fundamentally flawed - they did not treat the whole skin system and could not restore health to it long-term. So we continued in the ‘flare and repair’ cycle.

I knew from my time in the microbiology lab that our skin relies on its microbiome for environmental protection, moisture, healing, and a host of other necessary functions. 

A solution that incorporates the microbiome is going to be more effective and have fewer side effects. That is why there is so much interest in prebiotics as a ‘whole system’ answer to skin concerns.

But the so-called ‘innovation’ around the microbiome in skincare was not living up to its promise. Once again, products are relying on the same old active ingredients, just reformulated with a general prebiotic. Or worse, they make specious claims regarding probiotics or postbiotics. 

I knew what was possible with prebiotics: to feed the microbiome in a targeted and healthy way to induce it to work together with the body to produce the healthy skin we so desperately wanted. 

So I founded Rulo Skin, and together with my amazing team, we have developed revolutionary, proprietary prebiotics that are backed by science. 

Our commitment that comes with every product we produce: a product will not get the Rulo label unless it has high effectiveness and well thought out long-term impacts on the body, microbiome ecosystem, and the environment. 

In the end, we want long-term, effective products that restore health. We don’t add ingredients for marketing purposes, we add them because we know they work. 

Our customers are our family, and we hear them describing us as ‘the long-term, healthy skin company’ and that is truly the goal.

-- Dr. Nicole Scott

Our vision is that someday all people will have their healthiest, happiest skin.

Prebiotics

Why are our products special?

What Are Prebiotics? And What Is CeraBloom™?


You may have heard the term prebiotics in skincare, but what they actually do is often misunderstood.

So, what are prebiotics?

Prebiotics are nutrients that feed microbes.

On your skin, they serve as food for the organisms that make up your skin microbiome.

When the right microbes are supported, they help maintain a strong barrier, calmer skin, and better overall balance. But most skincare prebiotics—usually borrowed from the food world—feed microbes broadly and non-selectively.

Your skin microbiome is much more specific.

And that’s exactly why CeraBloom™ is different.

Meet CeraBloom™: A Precision Prebiotic Discovered with AI

CeraBloom™ isn’t a generic prebiotic.

It was discovered using our AI microbiome platform, which mapped the complex interactions between skin microbes and identified the exact nutrient that fuels the organisms linked to healthier, more resilient skin.

What CeraBloom™ does on your skin

CeraBloom™ feeds specific microbes on your skin—key organisms that naturally produce a diverse, skin-relevant set of specific and diverse ceramides.

These natural ceramides help:

Restore and strengthen your skin barrier
Reduce the appearance of redness and sensitivity
Re-balance your microbiome toward a healthier community
Improve skin resilience over time

And this isn’t theoretical. It’s clinically validated.

Backed by Three Clinical Trials

(including a nearly 80-person, 8-week randomized placebo-controlled study).
We know exactly what CeraBloom™ does on real skin because we tested it thoroughly:

3 completed clinical trials
One of the largest prebiotic skincare trials conducted (~80 participants)
✔ Showed improvements in barrier strength, redness, sensitivity, and overall skin health
✔ Demonstrated healthier, more diverse microbiome patterns
✔ Confirmed CeraBloom™ increases microbe-driven ceramide production on skin

CeraBloom™ has one of the most robust evidence bases of any microbiome-focused skincare ingredient.

Why Ceramides Matter

—and why feeding the right microbes changes everything!

Ceramides are essential lipids that keep your barrier strong, hydrated, and calm. As we age or experience sensitivity, ceramide levels drop and the barrier weakens.

Most skincare products try to add ceramides from the outside.

CeraBloom™ works differently:

It helps your skin make its own ceramides—naturally.

By feeding the microbes that produce a targeted,diverse set of ceramides, CeraBloom™ supports barrier repair from within the microbiome.

Why CeraBloom™ Isn’t a Typical Prebiotic

Traditional prebiotics:

Feed microbes broadly
Aren’t designed for skin
Can support unwanted organisms
Deliver limited or inconsistent results

CeraBloom™:

Discovered with our AI microbiome platform
Feeds specific target microbes tied to skin health
Boosts natural ceramide production
Re-balances the microbiome without overfeeding opportunistic species
Clinically proven improvements in barrier, redness, and sensitivity

It’s the first prebiotic designed for sensitive and aging skin with real mechanistic and clinical proof behind it.

The Bottom Line

Prebiotics feed microbes.

CeraBloom™ feeds the right ones.

Discovered using AI and validated across three clinical trials, CeraBloom™ supports the organisms on your skin that naturally make the ceramides your barrier needs to stay strong, calm, and resilient.

If you want skincare that works with your skin biology—not just on top of it—CeraBloom™ is the breakthrough.


Your microbiome is the community of bacteria, single-celled organisms, and viruses that live on your skin and are nearly everywhere!