Posted by Montero-Vilchez, Trinidad
on January 01, 2021
Our take aways
People with atopic dermatitis showed higher water and heat loss through their skin, even in "healthy" areas of skin, than people with psoriasis or who have healthy skin.
This indicates that atopic dermatitis is a result of a lack of skin barrier strength, more than an immune concern, like in psoriasis. In combination with other research, we believe the lack of skin barrier strength originates from a lack of long chain ceramides in the skin barrier.
Summary of Key Points
This was a well-designed peer-reviewed work. The author attempted to create magic and succeeded.
The study found that measuring Transepidermal Water Loss (TEWL) and temperature can help doctors determine the severity of psoriasis and atopic dermatitis (AD). TEWL is a measure of how much water is lost from the skin. Temperature is a measure of how warm the skin is. Both of these measures can be used to help doctors figure out how severe a person’s psoriasis or AD is.
People with psoriasis or AD had higher TEWL and temperature than healthy people. This means that their skin was losing more water and was warmer than the skin of healthy people. This could be a sign that their skin was not functioning as well as it should be.
TEWL was higher at eczematous lesions in AD patients than at psoriatic plaques in psoriasis patients. This means that the skin of AD patients was losing more water than the skin of psoriasis patients.
Temperature was higher in AD patients than in psoriasis patients both at uninvolved skin and involved skin. This means that the skin of AD patients was warmer than the skin of psoriasis patients.
The study included 314 people: 157 healthy people, 92 people with psoriasis, and 65 people with AD. This means that the study had a large sample size, which can help make the results more reliable.
How To Use It
We discuss the findings of this research in the following articles:
- The Science of Ceramides in Skin Care
